An overview of epidemiological and clinical characteristics of children with COVID-19 in Beijing. About 14% of patients showed positive again in the viral nucleic acid test after discharge. This study are helpful for the prevention and control of COVID-19 in children.

As the most common subtype of pediatric rhabdomyosarcoma (RMS), the prognosis of embryonal RMS has rarely been investigated solely. We utilized SEER database from 1988 to 2016 and assessed the impact of age, sex, race, tumor site, tumor stage, and treatment received on the prognosis of pediatric RMS.

The aim of this study was to assess the contribution of amide proton transfer-weighted (APTw) imaging and magnetization transfer (MT) imaging to the evaluation of children with developmental delay (DD). The most noteworthy finding of the present study is the significant differences in the MTR and APTw values between DD pediatric patients with delayed myelination on MRI and age-matched normal controls.

This review describes that although there are many challenges, for evaluating antiviral agents against SARS-CoV-2, researchers still need to use rigorously designed randomized controlled trials (RCTs). Remdesivir is the only antiviral agent that is effective and safe against the virus confirmed by evidences from RCT. Five RCTs failed to confirm efficacy and safety of chloroquine or hydroxychloroquine in treatment of COVID-19.

This review summarizes SARS-CoV-2 antagonize the innate immune response key component type I interferon and the efficacy and safety of type I interferon clinical studies on treatment and prevention of COVID-19.

This review mainly describes the cellular immunological features of COVID-19, including an uncontrolled innate immune response leading to cytokine storm, and severe lymphopenia and exhaustion of T cells. The potential COVID-19 immunotherapeutic approaches mainly targeting at blocking inflammatory cytokines and restoring immune cell function have been extensively investigated with many ongoing clinical trials.